LCP2 MaxPab mouse polyclonal antibody (B01)
产品名称： LCP2 MaxPab mouse polyclonal antibody (B01)
英文名称： LCP2 MaxPab mouse polyclonal antibody (B01)
产品编号： H00003937-B01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human LCP2 protein.
- Immunogen:
- LCP2 (NP_005556, 1 a.a. ~ 533 a.a) full-length human protein.
- Sequence:
- MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of LCP2 expression in transfected 293T cell line (H00003937-T01) by LCP2 MaxPab polyclonal antibody.
Lane 1: LCP2 transfected lysate(58.63 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3937
- GeneBank Accession#:
- NM_005565
- Protein Accession#:
- NP_005556
- Gene Name:
- LCP2
- Gene Alias:
- SLP-76,SLP76
- Gene Description:
- lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
- Omim ID:
- 601603
- Gene Ontology:
- Hyperlink
- Gene Summary:
- SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function. [provided by RefSeq
- Other Designations:
- 76 kDa tyrosine phosphoprotein,SH2 domain-containing leukocyte protein of 76kD,lymphocyte cytosolic protein 2,lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD)
- Related Disease