Anti-HR Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002396P-50ul	solarbio	50ul	960.00元
K002396P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-HR Polyclonal Antibody
别名	ALUNC;AU;HSA277165;HYPT4;MUHH;MUHH1
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	127kDa
Gene ID	55806
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human HR
性状	液体
Public Immunogen Range	Recombinant protein of human HR
Subcellular Locations	Nucleus
Swiss Prot	O43593
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene.